Vitamin D: Striking the Perfect Balance for Optimal Health
- Marisa Goncalves
- Nov 27, 2023
- 4 min read
(4 minutes reading)

We are all aware of the importance of obtaining sufficient vitamins and minerals for maintaining good health, and there exists a lengthy list of vital nutrients.
One frequently discussed nutrient is Vitamin D, which plays a crucial role in aiding the body's absorption of calcium, a mineral essential for strong bone development.
Vitamin D is also necessary for the proper functioning of the heart, muscles, nerves, and immune system, which relies on it to combat infections. However, determining the appropriate dosage can be a challenge.
Dr. Joann Manson, an expert on Vitamin D from Harvard University, emphasizes that we only require modest to moderate quantities of Vitamin D, rather than excessive mega-doses. According to current recommendations, adults should aim for a daily intake of 600 to 800 International Units (IUs) of Vitamin D. Failing to meet these levels can lead to serious health complications, such as inadequate bone development in children or the development of fragile bones and osteoporosis in adults.
It is imperative to ensure that you are receiving adequate Vitamin D, although researchers are discovering that more isn't necessarily better.
But where can you obtain it?
Vitamin D can be obtained from sunlight and your diet. Your skin produces Vitamin D when exposed to sunlight, particularly UVB light. However, many individuals do not spend enough time outdoors to meet their Vitamin D needs in this way.
It's worth noting that factors like clothing and sunscreen can inhibit the skin's production of Vitamin D when exposed to sunlight, and the level of melanin in your skin also plays a role. Melanin, responsible for skin color, results in darker skin tones when present in higher quantities, reducing the body's ability to produce Vitamin D from sunlight. This may increase the risk of Vitamin D deficiency.
Sunlight exposure isn't the sole means of obtaining Vitamin D. It is naturally found in certain foods, such as fatty fish, and is added to many fortified foods and dairy products.
As we age, our skin's ability to synthesize Vitamin D declines, as noted by Dr. Sarah Booth, a nutrition researcher at Tufts University. Older adults may also be less inclined to spend time outdoors. While experts do not generally recommend Vitamin D screening for healthy individuals, it is advisable to consult with a healthcare professional if you belong to a high-risk group.
Is more really better?
For the past three years or so, the marketing of vitamin D has been running at full throttle, yielding significant results. Few people, even after a routine medical consultation, end up not buying a Vitamin D supplement. There is a widespread belief that vitamins are always good. Well, it seems that the scientific community is not so sure about that yet.The question of whether "more is better" was addressed in a large clinical trial conducted by Dr. Manson and her team, known as VITAL.
The study sought to determine if Vitamin D supplements could reduce the risk of various health issues. Over 25,000 participants in the United States were randomly assigned to two groups: one received Vitamin D supplements, and the other received a placebo (an inactive pill with a similar appearance). After five years, both groups exhibited similar risk levels for most of the health conditions studied, including heart disease, cancer, depression, and bone fractures. According to Manson, the majority of healthy individuals did not benefit from Vitamin D supplements, but the study did not find any risks associated with the tested dose of 2000 IUs per day.
Additional research has indicated that moderate daily doses are safe over the long term. However, Manson cautions that higher doses carry potential risks, with the upper daily limit for Vitamin D set at 4,000 IUs. Exceeding this limit may lead to side effects such as kidney stones, nausea, vomiting, and muscle weakness. Excessive Vitamin D intake is often a consequence of excessive supplement usage. Nevertheless, for individuals unable to obtain sufficient Vitamin D from sunlight or their diet, moderate use of Vitamin D dietary supplements can help prevent deficiency.
Ongoing research continues to explore the various ways in which Vitamin D can benefit health, as it plays a role in numerous bodily functions. For instance, Manson's team is further investigating their VITAL findings, which suggest that Vitamin D supplements may lower the risk of autoimmune diseases or advanced cancer. They are also researching whether Vitamin D can reduce the risk of COVID-19 infection, severe COVID symptoms, and Long COVID.
Dr. Booth and her team recently discovered that older adults with higher Vitamin D levels in their brains had a reduced risk of dementia. However, the study couldn't confirm whether Vitamin D directly caused this lower risk. Further research is underway to gain a better understanding of Vitamin D's impact on brain health. Booth believes that the answer is likely complex, emphasizing that while Vitamin D is important, there is no evidence to suggest that a single nutrient can halt cognitive decline or prevent Alzheimer's disease.
Another research team, led by Dr. Sushil Jain at Louisiana State University, is investigating the link between diabetes, Vitamin D, and a molecule called glutathione. Glutathione assists the body in utilizing Vitamin D efficiently. Black Americans have a relatively higher risk of both Vitamin D deficiency and diabetes, and they are also more likely to have lower glutathione levels. Jain's team is studying whether boosting both glutathione and Vitamin D levels can help prevent diabetes in Black participants.
For the time being, individuals concerned about their Vitamin D levels can benefit most from adopting a healthy lifestyle, as outlined by Manson. This includes spending time outdoors, engaging in physical activity, avoiding smoking, and consuming a diverse range of nutritious foods rich in Vitamin D. While dietary supplements should never be considered a substitute for a healthy diet and lifestyle, they can be beneficial in certain circumstances.
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